New screening method to detect carriage of carbapenemase-producing Enterobacteriaceae in patients within 24 hours.

نویسندگان

  • N M Hanemaaijer
  • R H T Nijhuis
  • B J Slotboom
  • E M Mascini
  • A A van Zwet
چکیده

Rapid identification of patients colonized with carbapenemase-producing Enterobacteriaceae (CPE) is essential to prevent introduction and the spread of CPE in the hospital. This article presents the results of a new screening method to detect patients colonized with CPE within 24h after hospital admission. From high-risk patients rectal and throat swabs were collected and incubated overnight, after which DNA was isolated and tested for the most prevalent CPE genes (KPC, NDM, OXA-48, VIM and IMP) by a ligation-mediated real-time polymerase chain reaction. In 14 months 454 patients were screened; in six patients CPE were detected (carriage rate 1.3%).

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عنوان ژورنال:
  • The Journal of hospital infection

دوره 87 1  شماره 

صفحات  -

تاریخ انتشار 2014